Plasma pens ionize gas, such as air or noble gases, under normal [atmospheric] pressure conditions using electrical discharges. (Credit: PVA TePla)

Plasma pens integrated into production lines provide targeted plasma treatments that reduce failure rates by improving adhesion and bonding in various critical applications.

Plasma is a state of matter, like a solid, liquid, or gas. When sufficient energy is applied to a gas, it becomes ionized, transitioning into the plasma state. With precise application and control, plasma can alter surface properties of a metal or plastic part without compromising the underlying material.

Plasma contains ions, electrons, neutral particles, and reactive species that can be utilized for precision cleaning, decontamination, increasing surface wettability and other surface modifications. These techniques can boost the bond strength by up to 50 times in certain cases.

Often, plasma pens are incorporated into automated inline manufacturing processes or are controlled by robots. (Credit: PVA TePla)

While there are multiple methods for applying plasma to a medical device’s surface, one of the most popular and accessible are plasma pens. These tools ionize gas, such as air or noble gases, under normal atmospheric pressure conditions using electrical discharges. The plasma produced from the tip of the pen can be applied to very specific areas, or the entire part. Often plasma pens are incorporated into automated inline manufacturing processes or controlled by robots.

In medical device manufacturing today, plasma pens are widely used to improve adhesion in a broad range of critical applications. Their ability to activate, clean, and functionalize surfaces without the need for solvents makes them particularly valuable in a field where cleanliness, precision, and biocompatibility are paramount. These handheld or automated tools are used to prepare surfaces of polymers, metals, glass, and ceramics before bonding, coating, printing, or molding, ensuring strong, reliable adhesion in both permanent and temporary assemblies.

In catheter production, for example, plasma pens are used to improve the bond strength between polymer tubing and connectors or coatings, which is essential for both mechanical performance and fluid compatibility. In surgical instruments, diagnostic devices, and wearable monitors, plasma treatment enhances the adhesion of adhesives used to assemble housings, attach sensors, and apply protective coatings. It is also used to improve ink adhesion in the printing of lot numbers, calibration marks, or functional sensor inks on curved or irregular surfaces.

For implantable devices, plasma surface activation can be used to improve the bonding of encapsulants, coatings, or biointerfaces, while maintaining the strict cleanliness and non-contaminating requirements of medical-grade materials. It is also frequently employed to activate thermoplastics prior to over-molding or insert molding processes, enabling the formation of complex, multi-material components with strong interfacial adhesion.

Plasma pens are often integrated into cleanroom production lines, where their dry, noncontact operation is compatible with sterile environments. Their flexibility and precision make them particularly useful in prototyping and low- to medium-volume production, where design changes and varied geometries require adaptable surface preparation techniques.

While there are multiple methods for applying plasma to a product’s surface, one of the most popular and accessible are plasma pens. (Credit: PVA TePla)

Plasma pens serve as an affordable introduction to plasma technology. Unlike traditional vacuum-based plasma chambers where parts are processed in high-volume batches, the plasma pen can be installed inline and costs less, requires less energy, and incurs lower operational costs. Other advantages include reduced upfront investment, simplified exhaust management, and suitability for smaller-scale production requirements.

For manufacturers that only need to spot treat a part or operate high-speed production lines, a solution as simple as a pen may make more sense. A pen is also more affordable than a larger batch processing system.

Today, the use of plasma pens in medical device manufacturing is both extensive and growing, driven by the demand for miniaturized, high-performance devices that rely on flawless adhesion for safety, performance, and regulatory compliance.

Solving Complex Adhesion Challenges

For most applications, plasma treatments are utilized to increase the surface free energy of the material. Surface energy is defined as the sum of all intermolecular forces that are on the surface of a material, the degree of attraction or repulsion force of a material surface exerts on another material.

When a substrate has high surface energy, adhesives and other liquids often spread more easily across the surface. There are several mechanisms for increasing surface energy with plasma, including precision cleaning, chemically or physically modifying the surface, increasing surface area by roughening, and by applying primer coatings.

Most materials are initially hydrophobic [they repel water]. To make them bondable, their surface is typically modified to become hydrophilic [attract water. The plasma pen excels at making raw materials hydrophilic, enhancing their ability to bond effectively with chemical adhesives.

The plasma pen is particularly effective for preparing materials in overmolding processes, including polypropylene applications, dip coatings, or any method that involves encasing or encapsulating components. Enhancing the surface’s wettability allows the overmold to spread more effectively across the surface and minimizes the formation of bubbles or air gaps caused by low-energy surfaces. The result is a stronger and more reliable bond.

A common application of silicone overmolding is to safeguard electronic boards against exposure to humidity or outdoor weather conditions. Without proper adhesion, silicone can begin to delaminate, not only at the edges of the PCB board but also in the form of small air pockets on, or around, components. This can lead to moisture ingress and subsequent corrosion or electrical shorts.

Another challenge is the topography of a PCB, which means silicone must bond to many types of materials, including polymers, metals, alloys, ceramics, and the FR-4 board itself, all of which have unique surface energies and chemistries.

PVA TePla developed a specific process starting with a precision cleaning/surface activation treatment followed by the deposition of an inert chemical primer that serves as a tie layer for the overmolding and provides a uniform surface energy for the silicone to bond.

Plasma generated from atmospheric air exhibits strong oxidative properties, making it highly effective for surface cleaning and activation. Layers of absorbed molecules, such as oil and water on metallic surfaces, can be easily removed to improve adhesion.

Surface cleaning is also used in some cases to improve electrical contacts by cleaning oils and any organic debris from electrical contacts to ensure a better connection. One example is gold pads, the gold-plated contact points on a printed circuit board (PCB) that connect to other electronic components to transmit power, signals, and data. Other cleaning applications include wire and die bond pads, fiber optic cables, weld lines, and optics.

Atmospheric plasma can also be used to oxidize the surface of plastics to promote adhesion of materials like inks, adhesives, or coatings.

Plasma Pen Selection

Atmospheric plasma pens can generate two forms of plasma: blown plasma and corona discharge.

Blown plasma is created at atmospheric pressure and expelled through a nozzle using a carrier gas, typically air, nitrogen, or other inert gases. The gas flow produces a plasma plume capable of treating larger surface areas. PVA TePla’s PlasmaPen, for example, can deliver a directed beam 3–10 mm wide, with a plume length up to 14 mm.

The plasma produced from the tip of the pen can be applied to very specific areas, or the entire part. (Credit: PVA TePla)

Process gasses flow through the PlasmaPen assembly and are activated and ejected through the nozzle. The patented design keeps high voltages and current safely inside of the pen body, away from the plasma jet and substrate surfaces. The absence of electrical voltage in the plume allows heat-sensitive or electrically delicate materials like polymers, textiles, or electronics to be treated. Because the plume is electrically neutral, there is no risk of electrical arcing or damage to sensitive components.

Corona discharge plasma is the other alternative and is among the most commonly available pen types on the market. In this approach, a high-voltage electrical field is created to ionize a localized region of gas, creating plasma.

The strong electric field enables effective treatment of tough surfaces, and the discharge can be highly targeted, making it ideal for precision surface treatments in small or difficult-to-reach areas. However, the downside is the electrical discharge, which eliminates it from use in heat sensitive materials and sensitive materials.

In some systems, corona discharge can be blown by introducing a gas flow. This method is effective for covering larger areas or distributing energy more evenly. However, this approach has limitations, as the plume’s length is relatively short, and the process still relies on the presence of an electrical discharge.

Customization Options

Although plasma pens follow a standard design, significant variations exist between different models. Manufacturers like PVA TePla provide various options and customizations to meet specific needs, including adjustments to the aspect ratio of the plasma plume, intensity, and dwell times. When atmospheric plasma is delivered by a pen, a significant amount of heat is produced and it can cause scoring and marking of plastic or composite surfaces.

PVA TePla addressed the issue by designing a pen head with extra cooling channels to keep the tip cooler. The company also offers different pen tips to control the aspect ratio of the plasma plume. With a plasma pen, users need to be able to fine-tune the distance of the plume from the surface to control the intensity, while also considering the dwell time.

Even the angle of the approach can be a factor. If you are blowing plasma straight down at a 90° angle, you could potentially blow the contaminant that you are cleaning off back onto the surface. For this reason, PVA TePla recommends tilting the pen at a 30–60° angle so the plasma can bounce off the surface and leave a cleaner surface that is better for bonding.

Integration Options

Plasma pens can be seamlessly integrated into existing inline processes with varying degrees of automation. This flexibility is particularly beneficial, as plasma treatments are often introduced after initial processes have been validated, typically in response to high failure rates.

When more than a spot application is required, the pen can be programmed to raster back and forth over the surface to treat a complete part. Other alternatives include moving the pen by multi-axis robot around a stationary part; or keeping the pen stationary and moving/rotating the part.

Plasma technology has changed how manufacturers address persistent adhesion challenges, and plasma pens provide an accessible and cost-effective gateway for industries to harness its benefits.

By leveraging plasma pen technology into inline processes, medical device manufacturers can achieve stronger, more reliable bonds, improved wettability, and enhanced performance across various materials. With their ability to precisely treat surfaces, improve adhesion, and enhance surface energy, plasma pens have become an indispensable tool for the medical device manufacturing industry.

This article was written by Ryan Blaik, Sales Manager, PVA TePla, Corona, CA. For more information, contact Blaik at This email address is being protected from spambots. You need JavaScript enabled to view it. or visit here  .



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Medical Design Briefs Magazine

This article first appeared in the October, 2025 issue of Medical Design Briefs Magazine (Vol. 15 No. 10).

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