Tech Briefs

Briefs : Manufacturing & Prototyping
Controlling Heat Curing Adhesive Processes Using Infrared Spot Curing

Adhesives are often used as the joining compound between substrates in the medical device industry. Typical applications for adhesives include tube-to-connector bonding, steel-cannula-to-hub bonding, and any other joining process. Adhesives work particularly well in the...

Briefs : Medical
Precise Chemical Etching Method for Diamond Crystal Components

A new method developed at the National Institute of Standards and Technology (NIST) offers a precise way to engineer microscopic cuts in a diamond surface, yielding potential benefits in both measurement and technological fields.*

Briefs : Motion Control
Wireless Foot Switch Design Considerations

Wireless foot switches for the control of medical devices are gaining acceptance and growing in popularity — prompting OEMs to design medical equipment for use with a wireless foot switch or to accept a wireless foot switch as a pre-sale or post-sale option.

Briefs : Imaging
Spatially-Invariant Vector Quantization for Image Analysis

Researchers at the University of Michigan Health System and their colleagues have developed a software tool that aims to make the detection of abnormalities in cell and tissue samples faster, more accurate, and more consistent. The technique, known as Spatially-Invariant Vector...

Briefs : Materials
Benefits of Polypropylene Availability

Material selection plays an important role in the design of a medical device or bioprocessing system. It can improve end-user satisfaction, product reliability, and manufacturability of the device, as well as simplify the 510(k) application process. Various certifications such as animal-derivative-free, USP...

Briefs : Medical
Benefits of a Fully Digital Comparator for Inspection of Orthopedic Implants

Manufacturers of orthopedic implants take great care to ensure that their products are of the highest quality. One way they do this is by performing numerous inspection operations at various stages throughout the manufacturing process. These have great value —...

Briefs : Photonics/Optics
Tryptophan Fluorescence of Ocular Lens Protein for Early Diagnosis of Cataracts

Cataracts are the leading cause of blindness worldwide; they affect more than 20 million people and result in ~1.3 million operations annually in the United States. Current methods of cataract detection are based on subjective observation of lens opacity by Rayleigh...

Briefs : Medical
Versatile, Ceramic, Metering Pumps for Medical Applications

From R&D in the laboratory to production process control, from disposable component assembly to OEM diagnostic instrumentation, a broad array of medical and medical support applications rely on precise dispensing or metering of fluids. But just as diverse as the applications are the...

Briefs : Medical
Pulse Oximeter for Mobile Phone Platforms

Pulse oximetry non-invasively measures blood oxygen saturation (SpO2) and heart rate using a photo sensor to track the amount of absorbed light emitted by a red and infra-red LED. It allows for the rapid diagnosis of hypoxemia (low blood oxygen levels), which is difficult to identify...

Briefs : Medical
Multi Bore Flow Restrictor

Accuracy and reliability are key issues in the medical device industry — especially regarding administration of medical fluids or gases. Many medical fluid administration sets are provided with a flow restrictor. So far, a glass capillary is usually applied. However, this component has many shortcomings. The multi...

Briefs : Materials
Bionanomatrix Coating Boosts Biocompatibility of Implants

Cardiovascular stents and other medical implants increase lifespan and quality of life for millions around the world — yet adverse effects attenuate their full potential. Bionanomatrix coatings for such devices can vastly improve long-term outcomes.

Briefs : Electronics & Computers
Thermal Management Solutions for Medical Applications

Thermal management of medical electronic devices and systems is now more challenging. Power densities continue to increase while product form factors continue to shrink. Simple thermal management solutions, such as passive cooling (adding a fan and heat sink), are no longer typically viable...

Briefs : Medical
High-Resolution Ophthalmic Ultrasound System for Ocular Structures

An ophthalmic ultrasound system evaluates ocular structures more clearly by providing images of all aspects of the anterior segment. It provides images of the eye and tissues around and behind the eye to determine the presence of pathology when doctors are prohibited from viewing...

Briefs : Medical
Improved Devices for Collecting Sweat for Chemical Analysis

Improved devices have been proposed for collecting sweat for biochemical analysis — especially for determination of the concentration of Ca2+ ions in sweat as a measure of loss of Ca from bones. Unlike commercially available sweat-collection patches used previously in...

Briefs : Software
Brain Sensing Technology Provides Real-Time Diagnosis

Every 21 seconds, someone suffers a serious brain injury, including stroke, trauma, or concussion. Until now, there has been no way to quickly and reliably diagnose these calamities.

Briefs : Medical
Principles, Techniques, and Applications of Tissue Microfluidics

The principle of tissue microfluidics and its resultant techniques has been applied to cell analysis. Building microfluidics to suit a particular tissue sample would allow the rapid, reliable, inexpensive, highly parallelized, selective extraction of chosen regions of tissue for...

Briefs : Medical
Technology Eliminates the Need for Pre-Wetting Cartridge Filters

There has been a long-term need in the filtration industry — particularly for a variety of life science applications — to eliminate the need for pre-wetting cartridge filters with alcohol before sending them to customers. It is not only an expensive, time-consuming process, but...

Briefs : Medical
Quantifying Risk in Various Methods of Continuous Monitoring

Worldwide, there is growing concern about how to protect public safety and increase cooperation among regulatory agencies to audit medical device companies and their suppliers. Regulatory agencies are increasingly looking to global organizations such as the Global Health Task Force...

Briefs : Medical
High-Performance Micro-Porous Fluoropolymer Plastics for Critical Applications

Polytetrafluoroethylene (PTFE) is a fully fluorinated polymer with exceptional chemical and physical properties: excellent chemical resistance, high temperature stability, good dielectric and nonstick properties and exceptional resistance to degeneration under severe...

Briefs : Medical
Cytometer on a Chip

A cytometer now under development exploits spatial sorting of sampled cells on a microarray chip followed by use of grating-coupled surface-plasmon-resonance imaging (GCSPRI) to detect the sorted cells. This cytometer on a chip is a prototype of contemplated future miniature cytometers that would be suitable for rapidly...

Briefs : Medical
Microgravity-Enhanced Stem Cell Selection

Stem cells, both embryonic and adult, promise to revolutionize the practice of medicine in the future. In order to realize this potential, a number of hurdles must be overcome. Most importantly, the signaling mechanisms necessary to control the differentiation of stem cells into tissues of interest...

Briefs : Medical
Diagnosis and Treatment of Neurological Disorders by Millimeter-Wave Stimulation

Increasingly, millimeter waves are being employed for telecomm, radar, and imaging applications. To date in the U.S, however, very few investigations on the impact of this radiation on biological systems at the cellular level have been undertaken. In the beginning,...

Briefs : Medical
Tear-Based Glucose Sensor for Diabetes Monitoring

Diabetic control typically requires daily monitoring of blood glucose levels. This involves finger pricking 2–10 times a day in order to obtain a sample for assay. Many find the finger prick tedious or painful and fall into noncompliance. Others may also dislike the assorted “paraphernalia”...

Briefs : Manufacturing & Prototyping
Maintaining Sterility Assurance Level in Medical Device Design

A medical device undergoing design and classified as sterile will be confronted with various obstacles, not the least of which is how to determine and maintain its proposed Sterility Assurance Level (SAL) as it approaches its ultimate goal: delivery to market.

Briefs : Electronics & Computers
Electrocardiography (ECG) Necklace

Integrated wearable monitoring systems based on body area networks (BANs) enable continuous, reliable, and long-term monitoring of physio- and biological signals on the move, leading to wearable health solutions for next-generation healthcare, wellness, and lifestyle. An electrocardiography (ECG) necklace has...

Briefs : Medical
Utilizing Machine Vision Engines for Advanced Quality Control and Object Detection

Incorporating machine vision engines into an OEM system with automated handling provides a wide range of benefits to the manufacturer. Machine vision engines are self-contained vision systems that include the optics, lighting, image sensor, electronics, and...

Briefs : Electronics & Computers
Experimental Walking Assist Device With Body Weight Support System

An experimental walking assist device has been developed to help support body weight and reduce the load on the user’s legs while walking, going up and down stairs, and in a semi-crouching position. The device reduces the load on leg muscles and joints (in the hip, knees, and...

Briefs : Medical
Wearable, Artificially Intelligent, Bionic Device

eLEGS is a wearable, artificially intelligent, bionic device that enables people with paralysis to stand up and walk again. The exoskeleton is battery-powered and rechargeable, fitting comfortably and securely over clothing.

Briefs : Medical
Miniature Atom-Based Magnetic Sensor

Researchers from the National Institute of Standards and Technology (NIST) and the German national metrology institute have used a miniature atom-based magnetic sensor to successfully track a human heartbeat, confirming the device’s potential for biomedical applications.

Briefs : Medical
Epiretinal Prosthesis Surgically Implanted in the Eye

In a healthy eye, the photoreceptors (rods and cones) on the retina convert light into tiny electrochemical impulses that are sent through the optic nerve and into the brain, where they are decoded into images. If the photoreceptors no longer function correctly — due to conditions such as...

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