Current transcranial color Doppler (TCD) transducer probes are bulky and difficult to move in tiny increments to search and optimize TCD signals. This invention provides miniature motions of a TCD transducer probe to optimize TCD signals.
The mechanical probe uses spherical bearing in guiding and locating the tilting crystal face. The lateral motion of the crystal face as it tilts across the full range of motion was achieved by minimizing the distance between the pivot location and the crystal face. The smallest commonly available metal spherical bearing was used with an outer diameter of 12 mm, a 3-mm tall retaining ring, and 5-mm overall height. Small geared motors were used that would provide sufficient power in a very compact package. After confirming the validity of the basic positioning concept, optimization design loops were completed to yield the final design.
A parallel motor configuration was used to minimize the amount of space wasted inside the probe case while minimizing the overall case dimensions. The distance from the front edge of the crystal to the edge of the case was also minimized to allow positioning of the probe very close to the ear on the temporal lobe. The mechanical probe is able to achieve a ±20° tip and tilt with smooth repeatable action in a very compact package. The enclosed probe is about 7 cm long, 4 cm wide, and 1.8 cm tall.
The device is compact, hands-free, and can be adjusted via an innovative touchscreen. Positioning of the probe to the head is performed via conventional transducer gels and pillows. This device is amendable to having advanced software, which could intelligently focus and optimize the TCD signal.
The first effort will be development of monitoring systems for space use and field deployment. The need for long-lived, inexpensive clinical diagnostic instruments for military applications is substantial. Potential future uses of this system by NASA and other commercial end-users include monitoring cerebral blood flow of ambulatory patients, prognostic of potential for embolic stroke, ultrasonic blood clot treatment, monitoring open-heart and carotid endarterectomy surgery, and resolution of the controversy regarding transient ischemic attacks and emboli’s role. Monitoring applications include those for embolism formation during diving ascents, changes in CBFV (cerebral blood flow velocity) in relation to cognitive function as associated with sick building syndrome or exposure to environmental and workplace toxins, changes of CBFV for testing and evaluating Gulf War Syndrome, and patients or subjects while moving or performing tasks.
This work was done by Robert Chin of GeneXpress Informatics, and Srihdar Madala and Graham Sattler of Indus Instruments for Johnson Space Center.
In accordance with Public Law 96-517, the contractor has elected to retain title to this invention. Inquiries concerning rights for its commercial use should be addressed to:
Indus Instruments
721 Tristar Drive, Suite C
Webster, TX 77598
MSC-24702-1
This Brief includes a Technical Support Package (TSP).
Hands-Free Transcranial Color Doppler Probe
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Overview
The document outlines the development and potential applications of the Hands-Free Transcranial Color Doppler (TCD) Probe, a technology created by the NASA Johnson Space Center. The TCD probe is designed to improve the monitoring of cerebral blood flow and other neurological diagnostics through a compact and user-friendly device.
The document begins by addressing the challenges associated with current TCD transducer probes, which are often bulky and difficult to maneuver for optimal signal acquisition. The new design incorporates a mechanical probe that utilizes spherical bearings and electromechanical motors, allowing for precise tilting and positioning of the TCD transducer crystal. This innovation enables a ±20° tip and tilt motion, facilitating better signal optimization in a compact form factor measuring 68.9 mm long, 36.1 mm wide, and 17.5 mm tall.
The TCD probe is equipped with a touch screen for hands-free operation, enhancing user experience and efficiency. Although no automated software has been developed yet, the design is adaptable for future integration of advanced software that could intelligently focus and optimize TCD signals. The document emphasizes the potential for further advancements in microelectronics and motors to enhance the probe's capabilities.
In terms of commercial applications, the document highlights a projected diagnostic market nearing half a billion dollars by the end of 2009, indicating significant commercial interest and potential for the TCD technology. GXI, the organization behind the development, aims to pursue opportunities in the TCD diagnostic market, with initial efforts focused on monitoring systems for space use and military applications. The need for long-lasting, cost-effective clinical diagnostic instruments in these fields is substantial.
Additionally, the document lists various potential uses for the TCD system, including monitoring cerebral blood flow in ambulatory patients, assessing the risk of embolic strokes, and monitoring during surgical procedures. Other applications include evaluating cognitive function related to environmental toxins and monitoring patients during physical activities.
Overall, the Hands-Free TCD Probe represents a significant advancement in neurological diagnostics, with promising applications in both clinical and research settings, particularly in aerospace and military contexts. The document serves as a technical support package, providing insights into the innovation's design, functionality, and market potential.
