Neutrons Settle Long-Held Debate on Cancer Drug Design

In just two neutron experiments, Oak Ridge National Laboratory scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers. The team used neutrons and x-rays to draw a roadmap of every atom, chemical bond, and electrical charge inside a key enzyme that belongs to a metabolic pathway that cancer cells dramatically overuse to reproduce. Watch this video to learn more.

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Modified Pacifier, AI Can Determine Newborns’ Nursing Mechanics

A modified pacifier combined with AI algorithms to analyze the data it produces could determine whether newborns are learning the proper mechanics of nursing. The device was made up of a simple pacifier, connected to a 36-in.-long tube connected in turn to a vacuum sensor and a chip that collects the data from the sensor. The data can help determine whether a surgical intervention is necessary.

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Why Omalizumab Has the Potential to Be a ‘Life-Changing’ Food Allergy Medication

Watch this video to see Robert Wood, director of pediatric allergy and immunology at Johns Hopkins, discuss results that suggest omalizumab has the potential to be a life-changing medication for patients with food allergy, including those with multiple food allergies. The researchers also found that omalizumab injections increased participants’ threshold reactivity not just to peanuts but to other common food allergens to levels that would protect most patients from reactions after accidental exposure.

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How TBP Helps with Skin Lesion Correspondence Localization

Longitudinal tracking of skin lesions is beneficial to the early detection of melanoma. However, it has not been well-investigated in the context of full-body imaging. Watch this video to see a novel framework combining geometric and texture information to localize skin lesion correspondence from a source scan to a target scan in total body photography (TBP).

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