Using chemical "nanoblasts" that punch tiny holes in the protective membranes of cells, Georgia Tech researchers have demonstrated a new technique for getting therapeutic small molecules, proteins, and DNA directly into living cells. The work is believed to be the first to use activation of reactive carbon nanoparticles by lasers for...

A new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could someday allow people without medical training to painlessly administer vaccines. The new patch could also help prevent unsafe reuse of hypodermic needles, particularly in parts of the world with poor medical...

An obstacle to successful cancer drug therapy is the existence of drug delivery barriers, which result in insufficient and heterogeneous drug delivery to the tumor tissue. This drug delivery problem not only limits the clinical application of existing chemotherapeutics,...

Silicon-based nanoporous particles as biodegradable drug carriers are advantageous in permeation, controlled release, and targeting. The use of biodegradable nanoporous silicon and silicon dioxide, with proper surface treatments, allows sustained drug release within the target site...

University of Florida engineers have developed a prototype of a "tattletale pill" by adding a tiny microchip and digestible antenna to a standard pill capsule. The prototype opens up the possibility that mass-produced pills will someday be equipped to inform doctors and loved ones that patients have ingested their medication.

Blood loss is a major cause of death among combat casualties, accounting for nearly half of all deaths on the battlefield. The great majority of these deaths is due to intracavitary hemorrhage that cannot be controlled by traditional methods such as tourniquets or pressure...

Johns Hopkins University researchers have developed biodegradable nanosized particles that can bypass the body's mucus secretions to deliver a sustained-release medication cargo. The nanoparticles, which degrade over time into harmless components, could someday be used to carry life-saving drugs to individuals...

Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both injectable and enteral methods. Since the oral mucosa is highly vascularised, drugs that are absorbed through the oral mucosa directly enter the systemic...

As the number of investigational and approved vaccines continues to increase, the frequency of vaccinations will soon reach a practical limit. The development of combination vaccines is a common practice that addresses the concern of repeated visits to the clinic by reducing the total number of...

Hospira (Lake Forest, IL) has introduced the GemStar® SP infusion system with GemStar™ Infusion Suite software. The system is designed to help caregivers better incorporate patient safety best practices at the patient’s bedside. The GemStar Infusion Suite software is a standalone PC-based application that enables efficient...