Treatment for certain diabetes cases involves constant monitoring of blood-glucose levels and daily insulin shots. But scientists are now developing a painless “smart” patch that monitors blood glucose and releases insulin when levels climb too high.
People with Type 1 or advanced Type 2 diabetes regularly prick their fingers to measure blood-sugar levels, and some patients must inject themselves with insulin when needed. But sometimes, despite a person’s vigilance, glucose levels can still get out of whack. The researchers wanted to come up with a simpler, more effective, shot-free way to manage diabetes.
The skin patch is covered in painless microneedles that are loaded with tiny insulin-carrying pouches. The pouches are engineered to break apart rapidly and release the insulin in response to rising glucose levels. Diabetic mice wearing the patch maintained consistent concentrations of insulin in their blood. When these mice received a shot of glucose, their blood sugar levels spiked initially, but then fell to normal levels within two hours.