Multilayer antibacterial coatings offer a prolonged effect and a universal spectrum of action. The coating is based on modified titanium oxide and several antiseptic components. The coatings can be used in modern implantology as a protective layer for the prevention of concomitant complications — inflammation or implant rejection.
The multilayer coating synthesizes the protective properties of nanoparticles, biopolymers, anticoagulants, and antibiotics. The antibiotic and silver nanoparticles provide an antibacterial effect, while heparin prevents bacterial cells from sticking to the tissue surface, which reduces the amount of antibacterial agent required.
The chemical composition of the resulting coating layers was carefully studied by the developers using infrared and x-ray photoelectron spectroscopy. Scientists have found out that the incorporation of therapeutic components occurs throughout the whole plasma-applied polymer layer.
According to the developers, the coatings can be used as an antibacterial implant modifier, allowing it to accelerate implantation by reducing the risks of associated inflammation and stimulating the growth of osteoblastic cells. Researchers are currently planning to move to the preclinical development stage.
For more information, visit here .