Nanotech-Based Optical Sensor Image
The sensor has high sensitivity and specificity to the spike protein RBD of SARS-CoV-2 as well as human coronavirus NL63. (Credit: Andrew Davis Tucker/UGA)

Researchers have developed a rapid test for COVID-19 using nanotechnology-based optical sensors. The sensor has high sensitivity and specificity to the spike protein RBD of SARS-CoV-2 as well as human coronavirus NL63.

The swab-based rapid test uses a UV spectrometer for spike protein detection. The test will cover all COVID-19 variants, as well as any future variants. The LSPR sensor has several advantages in rapid diagnostics of SARS-CoV-2. Highly sensitive, specific, and able to detect CoV-2 at picomolar concentrations in saliva, it’s rapidity at less than 20 minutes is as good or better than current diagnostic platforms including RT-qPCR, also known as the gold standard.

The researchers are developing a detector based on this work within $10, and the sensor will link to a smartphone app.

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