Regenerative vascular graft technology. (Credit: Secant Group)

Researchers have developed a game-changing technology to advance cardiovascular regenerative medicine with the development of a synthetic, small-bore, vessel that encourages endogenous regeneration and new vessel formation.

The technology is based on textile forming capabilities that can produce a hollow lumen construct that is infused with Secant’s proprietary Regenerez® bioresorbable polymer technology. The new small-bore vessel supports the regeneration of new vascular tissue structures without the need for cell seeding or biologic growth promoters.

In situ vascular regeneration, along with the elastomeric and immunomodulatory properties of the synthetic vessel, could solve the problems of vascular harvesting and the nonresorbable synthetic graft compliance mismatching seen with the current technology available for surgeons today. These regenerative grafts will offer unprecedented benefits for coronary artery bypass surgery, peripheral vascular disease, and renal disease treatments.