A surgical glue that can help join blood vessels and close wounds faster. (Credit: Nanyang Technological University)

Researchers have developed a new type of surgical glue that can help join blood vessels and close wounds faster and may also serve as a platform to deliver pain relief drugs. The glue can bond soft tissues, including muscle and blood vessels, even when their surfaces are wet. Named CaproGlu, it is activated by a low dose of ultraviolet (UV) light that cures it in seconds, turning it from a liquid glue into a solid but flexible biorubber — a biocompatible material that can be resorbed by the tissue after a few weeks.

The team showed in animal experiments that blood vessels can be rejoined with just four stitches and a mesh wrapper dipped in CaproGlu, compared to the usual eight stitches that are required for a reliable and unobstructed join. The CaproGlu is a one-pot liquid gel solution that comes ready-to-use. The authors estimate that this will reduce surgery time by 25 percent, as surgeons spend less time and effort stitching up blood vessels and tissues.

CaproGlu’s protein-free formulation exploits new crosslinking chemistry unaffected by gamma sterilization.

For more information, visit here .


Medical Design Briefs Magazine

This article first appeared in the October, 2020 issue of Medical Design Briefs Magazine.

Read more articles from this issue here.

Read more articles from the archives here.