Bayer MaterialScience (Pittsburgh, PA) has introduced a family of hydrophilic coatings that combine lubricity and hemocompatibility with the mechanical properties of polyurethane. They are used in medical devices such as guidewires, catheters, leads, and endoscopes. The coatings are custom-designed and are based on polyurethane coating technology. Two types of formulations are available: aqueous polyurethane dispersions and solvent-borne polyurethane solutions. They can be applied to various substrates by spraying, dipping, or other methods.