Polyzen (Raleigh, NC) provides medical product designers with an alternative to latex materials for the construction of low-pressure balloons. A series of polyurethane films can be thermoformed, then welded together to form a medical balloon that achieves high neck-to-body ratio. These balloons can be produced in any size and configuration as small as 0.200" and offered in 1:5, 1:10, and 1:20 neck-to-body ratios, and in any variation in between. The balloons are fully three-dimensional and can be produced in thicknesses ranging from 1 to 10 mils. With the patented process, Polyzen can offer 3D designs with pressures up to 5 psi. The seams are located inside the balloon rather than outside, making the devices suitable for in-patient applications. Unlike most latex balloons, they can be folded into a compact shape for easier insertion into the body cavity or structure.