Researchers are bringing together multiple areas of technical expertise to improve LVAD performance and outcomes. One team will develop a smart magnetically levitated (Maglev) drive system that can sense the body’s physiological changes and automatically adjust the pump speed to meet the patient’s daily output requirement, such as for exercising and sleeping.
The device’s blood compatibility also is expected to be significantly increased by applying special slippery hydrophilic coatings to LVAD components to reduce the risk of blood clotting.
Another group will use machine learning to optimize the LVAD design to decrease the risks of blood clotting and blood damage. The team also will develop a novel pump inlet design, inspired by current stent and transcatheter aortic valve technology, to remedy the common problem of clot formation where the blood flow enters the LVAD.
The teams then will combine their synergistic technologies into a new LVAD prototype device that will be tested both in a benchtop flow loop and in preclinical models. The LVAD would greatly reduce the complications associated with long-term mechanical circulatory support. (Image credit: Texas Heart Institute)
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