In late April, NASA announced the development of Ventilator Intervention Technology Accessible Locally (VITAL), a ventilator prototype designed specifically to address the COVID-19 pandemic. Since then, 28 manufacturers  around the world have been licensed to make the device. Now one of those licensees is preparing to begin production in Brazil.

Anvisa, Brazil’s counterpart to the U.S. Food and Drug Administration, announced approval of this effort during an Aug. 24 press conference with the licensee, a joint partnership between Russer, a medical device manufacturer, and CIMATEC (Manufacturing and Technology Integrated Campus), a nonprofit research and development institution.

“Throughout its history, NASA’s missions to explore off Earth have benefited life on Earth and provided a means through which the United States has been able to strengthen relationships globally,” says NASA Administrator Jim Bridenstine. “During these difficult times, we are particularly proud that the unparalleled expertise, abilities, and passion of our workforce will aid other countries in their response to the coronavirus pandemic.”

This image shows the ventilator prototype for coronavirus disease patients designed and built by NASA's Jet Propulsion Laboratory in Southern California. (Credit: NASA/JPL-Caltech)

The ventilator prototype was designed at NASA’s Jet Propulsion Laboratory in Southern California, where spacecraft engineers felt compelled to contribute their know-how to address the pandemic. In just 37 days , they completed a functional prototype of VITAL, which received emergency use authorization from the FDA on March 24.

JPL ultimately created two versions of VITAL — a pneumatic version and another using compressed air. The CIMATEC/Russer version is based on the pneumatic version. With one-seventh the parts of a traditional ventilator, both versions models rely on parts readily available in supply chains to avoid competing for components required for traditional ventilators.

Designed specifically for the needs of COVID-19 patients, rather than the wide range of ailments treated with traditional ventilators, VITAL is simpler to build and more affordable. The CIMATEC/Russer model — which goes by the acronym VIDA, or “life” in Portuguese — will be available at a fraction of the cost of a traditional ventilator.

“This device benefits Brazil in multiple ways,” says CIMATEC Director Leone Andrade. “It can help Brazilians combat the virus while also providing an opportunity for industry.”

The 28 VITAL licensees were selected from 100 applicants based on their ability to manufacture and deliver the ventilator. Several other manufacturers around the world are far along in their own efforts to bring to market a version of the ventilator, with JPL providing technical guidance.

“Our team is delighted to see how quickly the Brazilian licensees were able to replicate our prototype design, upgrade it where necessary, and also obtain local regulatory approval,” says Leon Alkalai, manager of the JPL Office of Strategic Partnerships and VITAL project manager. “They did so in record time and we are truly impressed with how quickly they were able to master the art and even improve on the design.”

VITAL’s initial design, which CIMATEC/Russer’s model is based on, uses a pneumatic pump to circulate air into the ventilator and was run through a battery of tests by the Icahn School of Medicine at Mount Sinai in New York City. A modified design that relies on an air compressor could be deployed by a greater range of hospitals was tested at the UCLA Simulation Center in Los Angeles before also receiving a ventilator Emergency Use Authorization from the FDA.

For more information about NASA's work in fighting COVID-19, visit: .