Researchers from UNC-Chapel Hill and NC State University developed a new technology that will allow neuroscientists to capture images of the brain almost 10 times larger than previously possible – helping them better understand the behavior of neurons in the brain.
The researchers used a two-photon microscope, which images fluorescence, enabling them to see which neurons light up when active. The team designed a series of new lenses for the microscope and incorporated them into an overall two-photon imaging system that allowed the researchers to scan much larger areas of the brain. Instead of capturing images covering one square millimeter of the brain, they could capture images covering more than 9.5 square millimeters.