A new device that fits around the head like a halo, developed by a physician at the University of Arkansas for Medical Sciences and a researcher at the University of Arkansas at Little Rock, delivers therapy to quickly bust blood clots that could cause stroke. When ultrasound is typically used in combination with clot-busting drugs to treat stroke, there’s a big problem in getting the ultrasound to operate through the skull to deliver ultrasound to the vessels at the base of the brain. Bone typically blocks ultrasound waves.
Their ClotBust ER® device uses 16 transducers placed around the inside and designed to line up with the thin points in the skull, which allows the ultrasound waves to move through the brain without interruption. After the patient is administered an IV containing a drug, the circular device is placed onto the patient’s head like a sports visor or halo.
The use of ultrasound improves the clot-busting drug by 40 or 50 percent and the clot disappears more quickly, they said.
Now in a Phase Three human trial, the device has been tested in more than 300 patients, and 66 other university sites have signed up to be included in the testing. Their goal is to test 840 patients.