Medical Design Briefs

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A module employs highly complex pulse matching criteria and analysis tools and is suitable for challenging clinical environments.

Non-Invasive Blood Pressure (NIBP) is a widely used vital sign for cardiovascular assessment. Vital signs monitors obtain a non-invasive blood pressure measurement through the use of commercially available OEM blood pressure modules incorporated into their devices. These devices typically employ the oscillometric technique for the determination of blood pressure. NIBP devices approved for clinical use are tested for compliance to standards, including the AAMI/ANSI SP10-2002.
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A single-use, disposable device implants donor allograft tissue during endothelial keratoplasty.

Corneal endothelial failure is a common cause of corneal transplants. According to the Eye Bank Association of America, transplant tissue distributed for endothelial keratoplasty accounted for 18,221 (43%) of all keratoplasties performed in the US during 2009. Fuchs dystrophy, “other” causes, and post-cataract surgery edema were identified as the leading indications for endothelial replacement surgery. The leading indicator, Fuchs endothelial dystrophy, is an inheritable genetic condition that results in loss of endothelial cells and formation of an abnormal extracellular matrix.
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This technique provides detail and edge contrast enhancement, latitude reduction, and noise reduction when applied to digitizers for X-ray imaging.

Whenever images are acquired with a large dynamic range, a problem arises in reproducing these images on a medium (i.e. CRT, paper). There are the restrictions of the recording apparatus (number of reproducible intensity levels, color gamut, and color resolution) as well as environmental factors (flare, light level).
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This development represents an advancement in the field of portable microfluidic analysis systems, or lab-on-a-chip devices.

An advanced micro fluorescence detector (microFD) uses a hydrogenated amorphous silicon (a-Si:H) photodiode for high sensitivity biochemical analyses in micro-capillary electrophoresis (microCE) applications, representing an advancement in the field of portable microfluidic analysis systems, or lab-on-a-chip devices. The detector is highly sensitive to the emission wavelengths of commonly used fluorescent dyes, and in an integrated configuration using a Vertical Cavity Surface Emitting Laser (VCSEL) diode, proves efficacious for heavily multiplexed microfluidic biochemical analyses. This design can be fabricated and integrated at a low cost, making it ideal for the production of portable bioanalyzers that handle minute quantities of fluids (picoliters to nanoliters), as well as emerging large-scale integrated microfluidic technologies.
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